K9 Advantix II Large Dog 21–55 lbs – Flea and Tick | 2 Doses

K9 Advantix II Large Dog 21–55 lbs – Flea & Tick Protection – 2 Doses

Large Dog Flea & Tick Treatment 21–55 lbs – Monthly Topical Spot-On Protection

K9 Advantix II Large Dog 21–55 lbs Flea & Tick Treatment is a monthly topical flea and tick treatment for dogs 21–55 lbs. This 2-dose package helps protect large dogs against fleas, ticks, mosquitoes, and biting flies for up to 30 days per application when used as directed.

Designed for active large dogs, this waterproof monthly spot-on treatment provides convenient flea and tick protection without the need for collars or daily parasite control products. It is well suited for dogs that spend time outdoors, walk regularly in grassy or wooded areas, or are frequently exposed to fleas, ticks, mosquitoes, and biting flies.

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Key Benefits

• Weight-specific flea and tick treatment for large dogs 21–55 lbs
• Monthly topical protection against fleas, ticks, mosquitoes, and biting flies
• Helps control flea infestations by targeting multiple stages of the flea life cycle
• Fast and easy spot-on application with no daily flea control required
• Waterproof flea and tick protection — water-resistant after 24 hours from application and designed for monthly parasite protection
• Suitable for active dogs with regular exposure to outdoor areas
• 2-dose package provides two months of convenient monthly protection

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Why Choose K9 Advantix II Large Dog 21–55 lbs

• Provides convenient monthly protection without daily parasite treatments
• Helps protect dogs that spend time outdoors, including yards, parks, and trails
• Offers an easy alternative to flea and tick collars or frequent applications
• Works as a topical treatment applied directly to the dog's skin
• No prescription required when used according to label directions
• Suitable for both indoor and outdoor dogs exposed to fleas, ticks, mosquitoes, and other common parasites

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How It Works

K9 Advantix II Large Dog 21–55 lbs uses a topical formula applied directly to the dog's skin. After application, the active ingredients distribute through the skin surface and coat to help control fleas and ticks through contact.

The formula also helps repel mosquitoes and biting flies, providing additional protection for dogs exposed to outdoor environments.

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How to Use

• Apply the entire tube directly to your dog’s skin as instructed on the product label
• Part the fur until the skin is visible before application
• Place the applicator tip on the skin and squeeze the contents onto the recommended area
• Do not rub the treatment into the skin
• Repeat monthly to maintain continuous flea and tick protection

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Product Details

Brand: K9 Advantix II

Manufacturer: Bayer Animal Health / Elanco

Pet Type: Dog

Pet Size: Large Dogs (21–55 lbs)

Form: Topical spot-on liquid treatment

Quantity: 2 doses

Protection Duration: Up to 30 days per dose

Minimum Age: 7 weeks and older

EPA Reg. No.: 11556-143

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What’s Included

2 tubes (2-dose supply) of K9 Advantix II Large Dog 21–55 lbs

New, sealed, and factory fresh

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Warnings & Safety

• For external use only
• Do not use on puppies under 7 weeks
• Avoid contact with eyes or mouth
• Wash hands after application
• Consult a vet if your dog has health conditions

Keep out of reach of children

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You May Also Like

• K9 Advantix II Small Dog 4–10 lbs – Ideal for toy and small breeds needing fast-acting flea and tick protection tailored to their lower body weight.
• K9 Advantix II Medium Dog 11–20 lbs – Designed for mid-size dogs that require balanced, weight-specific parasite protection for indoor and outdoor activity.
• K9 Advantix II Extra Large Dog Over 55 lbs – Best for giant breeds with high outdoor exposure and thicker coats requiring stronger full‑body coverage.
• Seresto Large Dog Flea & Tick Collar – A long-lasting, low‑maintenance option providing up to 8 months of continuous protection for active large breeds.
• Frontline Plus Large Dog 45–88 lbs – A suitable alternative topical treatment for multi‑pet households needing rotation or separate protection for another dog.

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Disclaimer:

This product is intended for animal use only. Always follow label instructions. Results may vary depending on environment and level of infestation.

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Authenticity Guarantee:

We guarantee that all K9 Advantix II sold on our website are authentic, factory-sealed products in their original retail packaging.